Pd-catalyzed silicon hydride reductions of aromatic and aliphatic nitro groups.
نویسندگان
چکیده
[reaction: see text] Room-temperature reduction of aromatic nitro groups to amines can be accomplished in high yield, with wide functional group tolerance and short reaction times (30 min) using a combination of palladium(II) acetate, aqueous potassium fluoride, and polymethylhydrosiloxane (PMHS). Replacing PMHS/KF with triethylsilane allows aliphatic nitro groups to be reduced to their hydroxylamines.
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ورودعنوان ژورنال:
- Organic letters
دوره 7 22 شماره
صفحات -
تاریخ انتشار 2005